Dr Monica Arman Albert

Lecturer in Biomedical Sciences


Mònica obtained her PhD from the University of Barcelona in 2004 with a thesis that investigated the transcriptional regulation of the lymphocyte proteins CD5 and CD6. She then completed post-doctoral studies in the laboratory of Prof Alexandra Rowe, at the University of Edinburgh, where she investigated the interaction between Plasmodium falciparuminfected erythrocytes and platelets, and its association with severe malaria. She continued her post-doctoral training in the laboratory of Prof Steve Watson, at the University of Birmingham, where she studied the molecular pathways that mediate platelet activation by bacteria associated with sepsis and infective endocarditis. In 2015 she was appointed as a lecturer at Hull York Medical School.


Mònica’s research group is focused on understanding the molecular mechanisms that regulate platelet activation by bloodstream pathogens, including bacteria associated with cardiovascular pathology and malaria-causing Plasmodium falciparum parasites.


Selected publications

Research papers:

Watson CN, Kerrigan SW, Cox D, Henderson IR, Watson SP, Arman M. (2016). Human platelet activation by Escherichia coli: roles for FcγRIIA and integrin αIIbβ3. Platelets27(6), 535–540.

 Arman M, Krauel K, Tilley DO, Weber C, Cox D, Greinacher A, Kerrigan SW, Watson SP. (2014). Amplification of bacteria-induced platelet activation is triggered by FcγRIIA, integrin αIIbβ3, and platelet factor 4. Blood, 123(20): 3166-74.

Tilley DO, Arman M, Smolenski A, Cox D, O'Donnell JS, Douglas CW, Watson SP, Kerrigan SW. (2013). Glycoprotein Ibα and FcγRIIa play key roles in platelet activation by the colonizing bacterium, Streptococcus oralisJ Thromb Haemost, 11(5): 941-50

Arman M, Adams Y, Lindergard G, Rowe JA. (2013). A method for positive and negative selection of Plasmodium falciparum platelet-mediated clumping parasites and investigation of the role of CD36. PLoS One, 8(2): e55453.

Claessens A, Adams Y, Ghumra A, Lindergard G, Buchan CC, Andisi C, Bull PC, Mok S, Gupta AP, Wang CW, Turner L, Arman M, Raza A, Bozdech Z, Rowe JA. (2012). A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells. Proc Natl Acad Sci USA, 109(26): E1772-81.

Ghumra A, Semblat JP, Ataide R, Kifude C, Adams Y, Claessens A, Anong D, Bull P, Fennell C, Arman M, Amambua-Ngwa A, Walther M, Conway D, Kassambara L, Doumbo O, Raza A, Rowe JA. (2012). Induction of Strain-Transcending Antibodies Against Group A PfEMP1 Surface Antigens from Virulent Malaria Parasites. PLoS Pathogens, 8(4):e1002665.

Arman M, Aguilera-Montilla N, Mas V, Puig-Kröger A, Pignatelli M, Guigó R, Corbí AL, Lozano F. (2009). The human CD6 gene is transcriptionally regulated by RUNX and Ets transcription factors in T cells. Molecular Immunology, 46(11-12): 2226-35.

Arman M, Rowe JA. (2008). Experimental conditions affect the outcome of Plasmodium falciparum platelet-mediated clumping assays. Malaria Journal, 7:243.

Arman M, Raza A, Tempest LJ, Lyke KE, Thera MA, Koné A, Plowe CV, Doumbo OK, Rowe JA. (2007). Platelet-mediated clumping of Plasmodium falciparum infected erythrocytes is associated with high parasitemia but no severe clinical manifestations of malaria in african children. American Journal of Tropical Medicine and Hygiene, 77(5): 943-6.

Kyriacou HM, Steen KE, Raza A, Arman M, Warimwe G, Bull PC, Havlik I, Rowe JA. (2007). In vitro inhibition of Plasmodium falciparum rosette formation by Curdlan sulfate. Antimicrobial Agents and Chemotherapy, 51(4): 1321-6.

Arman M, Calvo J, Trojanowska ME, Cockerill PN, Santana M, Lopez-Cabrera M, Vives J, Lozano F. (2004). Transcriptional regulation of human CD5: important role of Ets transcription factors in CD5 expression in T cells. Journal of Immunology, 172(12): 7519-29.

Reviews and Book Chapters:

Arman M, Payne H, Ponomaryov T, and Brill A. (2015). Role of Platelets in Inflammation. Book Chapter In: Kerrigan S, Moran N eds. The Non-Thrombotic Role of Platelets in Health and Disease; ISBN 978-953-51-4091-7. In press.

Arman M and Krauel K. (2015). Human platelet IgG Fc receptor FcγRIIA in immunity and thrombosis. Journal of Thrombosis and Haemostasis13(6), 893–908.

Rowe JA, Claessens A, Corrigan RA, Arman M. (2009). Adhesion of Plasmodium falciparum-infected erythrocytes to human cells: molecular mechanisms and therapeutic implications. Expert Reviews in Molecular Medicine, 11:e16.