Graduated from Athens Medical School in 1983 and completed his medical training in internal medicine in 1990. In 1995 awarded PhD from the University of London on the application of radiolabeled monoclonal antibodies in the treatment of Head and neck Cancer. He subsequently became a lecturer at St George’s Hospital Medical School studying the application of allogeneic vaccines in Melanoma. Appointed Senior Lecturer in Medical Oncology at the University of Hull in 1999, helping establish the Cancer services for HEYCCN (Humber and East Yorkshire Coast Cancer Network) and the new Medical School of HYMS (Hull York Medical School). He was promoted to Reader in HYMS and subsequently Professor of Medical Oncology. He treats gastrointestinal cancers studying the impact of thrombosis on these patients, and has been PI for many trials in melanoma and renal cell carcinoma including being Co-I for the STAR trial in RCC. His basic research interests include the targeting of cancer neo-vasculature and the haemostatic apparatus to interfere with cancer metastasis.