Professor Charles Lacey

MD, FRCP

Professor of Medicine

Role at Hull York Medical School

I am a clinical academic involved in research and teaching.

Biography

Charles Lacey is Professor of Medicine at Hull York Medical School, and Honorary Consultant Physician at York Teaching Hospitals Foundation Trust. He qualified from Guy’s Hospital Medical School, University of London, and undertook postgraduate training in Bristol, Bath, and Cambridge. He was appointed Consultant Physician in Genitourinary Medicine at the Leeds General Infirmary in 1982, and there developed his interest in sexually transmitted disease research, being awarded grants from the YCRC and MRC to study HPV and candidosis. He also led and advised on HPV and HSV vaccine development in collaboration with industry. In 1996 he was appointed Senior Lecturer in Genitourinary Medicine and Communicable Diseases at Imperial College London, and Honorary Consultant Physician, St Mary’s Hospital, London. He worked in Jonathan Weber’s group, both on HPV clinical and laboratory studies, and also developed a vaginal microbicide research programme, gaining funding from MRC, EC and NIH. In 2004 he moved to Hull York Medical School, initially as Reader, and then was appointed to the first Chair in Clinical Medicine in York in 2007.

Research

Charles is a member of the Experimental Medicine and Biomedicine research group.

In HPV, with colleagues, we are currently carrying a multi-arm HPV vaccine study including evaluating one dose regimes in schoolgirls in Tanzania. In York we are conducting memory B cell assays across the trial arms. In York we are also developing a new non-invasive anal neoplasia cytology assay as part of a prospective anal cancer screening study.In Leishmaniasis, we are conducting RCTs in Sudan evaluating our vaccine (ChAd63-KH) for both prevention and treatment of post-kala azar dermal leishmaniasis. We are also working with colleagues in Ethiopia, Uganda, Kenya and Sudan to evaluate systemic and cutaneous immune responses and parasite load during treatment of visceral leishmaniasis. In York, we are developing a human challenge model of Leishmania major infection.

Teaching

I teach medical and postgraduate students on various aspects of infectious diseases, HIV and vaccinology.

Publications

Visit Professor Charles Lacey's profile on the York Research Database to see a full list of publications, browse activities and projects, and explore connections, collaborators, related work and more.

Collaborations
  • London School of Hygiene & Tropical Medicine
  • University College London
  • National Institute of Medical Research, Tanzania
  • Institute for Endemic Diseases, University of Khartoum, Sudan
Postgraduate research supervision

I welcome enquiries from prospective postgraduate research students.

I supervise one PhD student, Dr Vivak Parkash, at present.

External roles

I sit on the NIHR Infection Speciality Committee, and the BASHH HPV Special Interest Group.