Professor Una Macleod




Una Macleod became Dean of the Hull York Medical School on 1st January 2017. She joined the medical school in 2010 as Professor of Primary Care Medicine and had previously worked in Glasgow, where she trained in Medicine and had been Senior Lecturer in General Practice and Primary Care and a half-time GP principal in the east end of the city. Her research interests revolve around primary care and cancer, and health inequalities. She is a national leader in the area of cancer and early diagnosis research, has contributed significantly to policy development, and holds or has held grants from Cancer Research UK, Yorkshire Cancer Research and the Department of Health Policy Research Unit programme in this area. She continues to work clinically as a GP at Bransholme Health Centre in Hull.


Current research projects include:

EMPRESS: Cancer diagnosis via Emergency Presentation: a case control Study £343,755 funded by Cancer Research

TRANSFORM: Reducing inequalities in cancer outcomes in Yorkshire: Realising our potential for innovation in diagnosis, patient management, survivorship and palliative care research. £4.9m, funded by Yorkshire Cancer Research

PEOPLE-HULL: Primary care and community Engagement to Optimise time to Presentation with Lung cancEr symptoms in HULL.  £712,501, funded by Yorkshire Cancer Research

Using primary care to increase uptake of the Bowel Scope Screening Programme in Hull: evaluating paper and telephone-based interventions.  £349, 944, funded by Yorkshire Cancer Research (PI L McGregor, Stirling)

REviewing long term anti-Depressant Use by Careful monitoring in Everyday practice (REDUCE) programme. NIHR Programme Grants for Applied Research  2016-2021, £2,244,889. (PI T Kendrick, Southampton)

CPR for cancer outcomes - comprehensive patient records (CPR) to define the impact of cancer, co-morbidities and late effects on individuals and the health service.  Funded by Macmillan Cancer Support  £689,000, (PI A Glaser, Leeds)

Integrated therapist and online CBT for depression in primary care. NIHR Programme Grants for Applied Research, £2,218,726 (PI N Wiles, Bristol)


Una Macleod contributes to the Phase 1 Scholarship and Special Interest Programme on cancer screening, awareness and detection. She also lectures on NHS cancer policy and health inequalities.

  • Tallon D, Wiles Nicola, Campbell J, Chew-Graham C, Dickens C, Macleod U, Peters TJ, Lewis G, Anderson IM. Gilbody S, Hollingworth W, Davies S, Kessler D.  Mirtazapine added to selective serotonin reuptake inhibitors for treatment-resistant depression in primary care (MIR trial): study protocol for a randomised controlled trial. Trials (2016) 17:66 DOI 10.1186/s13063-016-1199-2
  • Johnson MJ, Allgar Vi, Macleod U, Jones A, Oliver S, Currow D.  Family Caregivers Who Would Be Unwilling to Provide Care at the End of Life Again: Findings from the Health Survey for England Population Survey. PLoS ONE 2016: 11: e0146960.  doi:10.1371/journal.pone.0146960
  • Whitaker KL, Winstanley K, Macleod U, Scott SE, Wardle J. Low cancer suspicion following experience of a cancer ‘warning sign’.  European Journal of Cancer 2015;  51: 2473–2479.
  • Chen H, Nicolson D, Macleod U; Allgar V Dalgliesh C; Johnson M.  Does the use of specialist palliative care services modify the unfavourable effect of socioeconomic status on place of death? A systematic review. Palliative Medicine 2015; DOI: 10.1177/0269216315602590
  • Rubin G, Berendsen A, Crawford SM, Dommett , Earle C, Emery J, Fahey T, Grassi L, Grunfeld E, Gupta S, Hamilton W, Hiom S, Hunter D, Lyratzopoulos G, Macleod U, Mason R, Mitchell G, Neal RD, Peake M, Roland M, Seifert B, Sisler J, Sussman J, Taplin S, Vedsted P, Voruganti T, Walter F, Wardle J, Watson E, Weller D, Wender R, Whelan J, Whitlock J, Wilkinson C, de Wit N, Zimmermann. The expanding role of primary care in cancer control. Lancet Oncol 2015: 16: 1231–72
  • Williamson AE, Ayres R, Allen J, Macleod U.  Core intended learning outcomes for tackling health inequalities in undergraduate medicine. BMC Medical Education (2015) 15:66; DOI 10.1186/s12909-015-0342-1
  • Mitchell ED, Pickwell-Smith B, Macleod U. Risk factors for emergency presentation with lung and colorectal cancers: a systematic review.  BMJ Open 2015;5:e006965.doi:10.1136/bmjopen-2014-006965
  • Green T, Atkin K, Macleod U.  GPs’ perceptions and experiences of public awareness campaigns for cancer: a qualitative enquiry.  Health Expectations 2015; DOI: 10.1111/hex.12362
  • Dikomitis L, Green T, Macleod U.  Embedding electronic decision-support tools for suspected cancer in primary care: a qualitative study of GPs’ experiences.  Primary Healthcare Research & Development (2015), 1-8; doi:10.1017/S1463423615000109
  • Mitchell ED, Rubin GR, Merriman L, Macleod U.  The role of primary care in cancer diagnosis via emergency presentation: qualitative synthesis of significant event reports.  British Journal of Cancer (2015), S50-S56 doi: 10.1038/bjc.2015.42
  • Green T, Atkin K, Macleod U.  GPs and cancer recognition and referral in England: an in-depth study.  British Journal of Cancer (2015), S41–49; doi: 10.1038/bjc.2015.41
  • Neal RD, Tharmanathan P, France B, Ud Din N, Cotton S, Julia Fallon-Ferguson, Hamilton W, Hendry A, Hendry M, Lewis R, Macleod U, Mitchell ED, Pickett M, Rai T, Shaw K, Stuart N, Tørring ML, Wilkinson C, Williams B, Williams N, Emery J. Is increased time to diagnosis and treatment in symptomatic cancer associated with poorer outcomes? Systematic review.  British Journal of Cancer (2015), S92-1071–16, doi: 10.1038/bjc.2015.48
  • Whitaker K, Macleod U, Winstanley K, Scott SE, Wardle J.  Help-seeking for cancer ‘alarm’ symptoms: a qualitative interview study.  Br J Gen Pract 2015; DOI: 10.3399/bjgp15X683533.
  • Green T, Martins T, Hamilton W, Rubin G, Elliott K, Macleod U. Exploring GPs' Experiences of Using Diagnostic Tools for Cancer: a qualitative study in primary care. Family Practice 2014;doi: 10.1093/fampra/cmu081
  • Gadoud A, Kane E, Macleod U, Ansell P, Oliver S, Johnson M.  Palliative care among heart failure patients in primary care: a comparison to cancer patients using English family practice data. PLoS ONE 9(11): e113188. doi:10.1371/journal.pone.0113188
  • Whitaker K, Scott SE, Winstanley K, Macleod U, Wardle J.  Attributions of cancer ‘alarm’ symptoms in a community sample. PLoS ONE 9(12): e114028. doi:10.1371/journal.pone. 0114028
  • Browne S, Macdonald S, May CR, Macleod U, Mair FS.  Patient, Carer and Professional Perspectives on Barriers and Facilitators to Quality Care in Advanced Heart Failure. PLoS ONE 2014, 9(3): e93288. doi:10.1371/journal.pone.0093288
  • Howell DA, Smith AG, Jack A, Patmore R, Macleod U, Mironska E, Roman  E.   Time-to-diagnosis and symptoms of myeloma, lymphomas and leukaemias: a report from the Haematological Malignancy Research Network.  BMC Hematology.2013, 13:9. DOI: 10.1186/10.1186/2052-1839-13-9
  • Gray NM, Hall SJ, Browne S, Johnston M, Lee AJ, Macleod U, Mitchell ED, Samuel L, Campbell NC. Predictors of anxiety and depression in people with colorectal cancer. Support Care Cancer, DOI 10.1007/s00520-013-1963-8
  • Gray N M, Allan J L, Murchie P, Browne S, Hall S, Hubbard G, Johnston M, Lee A J, McKinley A, Macleod U, Presseau J, Samuel L, Wyke S, Campbell N C. Developing a community-based intervention to improve quality of life in people with colorectal cancer: a complex Intervention development study. BMJ Open 2013;3:e002596. doi:10.1136/bmjopen-2013-002596
  • Hamilton W, Green T, Martins T, Elliott K, Rubin G, Macleod U.  Evaluation of risk assessment tools for suspected cancer in general practice. Br JGenPract 2013 Jan e30-e36