This research focuses on negative pressure wound therapy (NPWT), a common treatment for chronic, non-healing wounds.
The researchers developed a new large-scale system to culture human skin outside the body (ex vivo) to effectively compare the effects of two different NPWT modalities: single-use and traditional devices.
These devices were applied to wounded skin samples and cultured for 48 hours.
The researchers then evaluated the skin's cellular response to the therapy through histological analysis (studying the microscopic structure of the tissues) and transcriptional profiling (studying the gene expression).
The research was likely conducted in the medical or healthcare industry, specifically in the field of wound care and treatment.