Our researchers are at the forefront of exploring the body's immune response, with a specific focus on the intricate dynamics of the skin and its interaction with infectious diseases.
Our ground-breaking studies in Leishmaniasis—a neglected tropical parasitic disease – have discovered the complex mechanisms underlying the skin's reaction to Leishmania infection, unveiling the pivotal roles played by specific proteins and cells. This understanding not only paves the way for new breakthroughs in Leishmaniasis treatment and vaccination, but also holds promise for combating a spectrum of similar diseases.
Additionally, our researchers study the Leishmania parasites, which cause a severe disease known as visceral leishmaniasis. Through our investigations, we have discovered the influential role of a key sensor—TORC1—in the growth and transformation of these parasites. This critical discovery sheds light on potential vulnerabilities that could be harnessed for more effective interventions against this disease.
Our expertise in immunology extends to the intersection of cancer biology and immune response. In particular, we have dedicated substantial efforts to unravelling the intricate involvement of microRNAs in cancer development and progression. These molecules hold immense potential for innovative cancer therapies and cutting-edge diagnostic tools. Our research not only deepens our understanding of the complex interplay between immunology and cancer, but also opens up exciting possibilities for personalised and targeted interventions.