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Technologies to improve drug delivery through aged skin and non-melanoma skin cancer


tarl prow

Professor Tarl Prow

Director, Skin Research Centre

Miko Yamada

Dr Miko Yamada

Research Fellow



About the research

This study is a comprehensive review of physical drug delivery enhancement technologies, with a particular focus on their application in treating UV damaged skin, actinic keratoses (a type of skin condition that can lead to cancer), and non-melanoma skin cancers.

The research examines the pros and cons of these technologies, their mechanisms of action, clinical efficacy, and experimental design. It also evaluates the outcomes reported in academic publications, clinical trial reports, and patents. 

Industry application

The research is relevant to the pharmaceutical and healthcare industries, particularly those involved in the development and application of cosmeceutical and skin cancer treatments.

Study findings

The study found that physical drug delivery enhancement technologies can significantly improve the effectiveness of cosmeceutical and skin cancer treatments. However, each approach has its own advantages and disadvantages.

The commercial success of these technologies in cosmeceutical applications, such as microneedles, is expected to drive further innovation in this field, potentially changing the way actinic keratoses and non-melanoma skin cancers are managed clinically. 


Yamada M, Prow TW. Physical drug delivery enhancement for aged skin, UV damaged skin and skin cancer: Translation and commercialization. Adv Drug Deliv Rev. 2020 Jan 1;153:2-17. doi: 10.1016/j.addr.2020.04.008. Epub 2020 Apr 24. PMID: 32339593.

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